Recombinant PI3 Kinase p85 alpha Monoclonal Antibody
This is a Recombinant PI3 Kinase p85 alpha Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of insulin and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer, which is composed of a P110 catalytic subunit and a P85 regulatory subunit, is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.
Synonyms
GRB1, p85 alpha, p85, P85A, Phosphatidylinositol 3 kinase associated p 85 alpha, Phosphatidylinositol 3 kinase regulatory 1, Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 1 (p85 alpha), Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha
Gene ID
5295
Swiss Prot
P27986
Reactivity
Human, Rat, Hamster
Immunogen
A synthetic peptide of human PI 3 Kinase p85 alpha
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000, IF 1:20-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
25kDa
Observed Molecular Weight
25kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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