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Recombinant ALDH1A1 Monoclonal Antibody

This is a Recombinant ALDH1A1 Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

ALDH1A1 (Aldehyde dehydrogenase family 1 member A1), also named as ALDC, ALDH1 and PUMB1, belongs to the aldehyde dehydrogenase family. The ALDH1A1 gene encodes a liver cytosolic isoform of acetaldehyde dehydrogenase, an enzyme involved in the major pathway of alcohol metabolism after alcohol dehydrogenase. ALDH1A1 plays a critical role in protection against oxidative stress-induced cytotoxicity in lens epithelial cells. And it is important for multiple biological activities including drug resistance, cell differentiation, and oxidative stress response. As a novel cancer stem cell marker, ALDH1A1 can be used for tumors whose corresponding normal tissues express ALDH1A1 in relatively restricted or limited levels such as breast, lung, ovarian or colon cancer.

Synonyms

ALDH1A1, ALDC, ALDH-E1, ALDH1, ALDH11, HEL-9, HEL-S-53e, HEL12, PUMB1, RALDH1

Gene ID

216

Swiss Prot

P00352

Reactivity

Human, Mouse

Immunogen

A synthetic peptide of human ALDH1A1

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, IHC-P

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

300 μg/mL

Dilution

WB 1:500-1:1000, IHC 1:20-1:100

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

84kDa

Observed Molecular Weight

84kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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