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CST3 Polyclonal Antibody

This is a CST3 Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus.

Synonyms

AD8, Amyloid angiopathy and cerebral hemorrhage, ARMD11, CST3 protein, Cystatin 3, CystatinC, Epididymis secretory protein Li 2, bA218C14.4, Gamma trace, HCCAA, HEL S 2, Neuroendocrine basic polypeptide, Post gamma globulin

Swiss Prot

P01034

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Human CST3 protein expressed by E.coli

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal antibody

Applications

WB, IHC

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000, IHC 1:250-1:500

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH 7.4

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

25 kDa

Observed Molecular Weight

26 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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