ALKBH5 Polyclonal Antibody
This is a ALKBH5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N (6-methyladenosine (m6A RNA, the most prevalent internal modification of messenger RNA (mRNA in higher eukaryotes. Can also demethylate N (6-methyladenosine in single-stranded DNA (in vitro. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export. Required for the late meiotic and haploid phases of spermatogenesis by mediating m6A demethylation in spermatocytes and round spermatids: m6A demethylation of target transcripts is required for correct splicing and the production of longer 3'-UTR mRNAs in male germ cells (By similarity.
Synonyms
ALKBH5, ABH5, OFOXD, OFOXD1
Gene ID
54890
Swiss Prot
Q6P6C2
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human ALKBH5
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
48kDa/53kDa
Observed Molecular Weight
48KDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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