RBFOX1 Polyclonal Antibody
This is a RBFOX1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U) GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2) . Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms
RBFOX1,2BP1, A2BP1, FOX-1, FOX1, HRNBP1
Gene ID
54715
Swiss Prot
Q9NWB1
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human RBFOX1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IF 1:100-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
16kDa/18kDa/60kDa/63kDa/65kDa
Observed Molecular Weight
66kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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