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PHGDH Polyclonal Antibody

This is a PHGDH Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.

Synonyms

PHGDH,3-PGDH,3PGDH, HEL-S-113, NLS, NLS1, PDG, PGAD, PGD, PGDH, PHGDHD, SERA

Gene ID

26227

Swiss Prot

O43175

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human PHGDH

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

33kDa/36kDa

Observed Molecular Weight

37kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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