Recombinant mtTFA Monoclonal Antibody
This is a Recombinant mtTFA Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. TFAM (Transcription Factor A, Mitochondrial) is a Protein Coding gene. Diseases associated with TFAM include Mitochondrial Dna Depletion Syndrome 15, Hepatocerebral Type and Skin Carcinoma In Situ. Among its related pathways are Mitochondrial Gene Expression and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include poly (A) RNA binding and chromatin binding.
Synonyms
Anscription factor 6-like 1, Mitochondrial transcription factor 1, mitochondrial transcription factor A, MtTF1, mtTFA, TCF 6, TCF-6, TCF6, TCF6L1, TCF6L2, TCF6L3, TFAM, TFAM, Transcription factor 6, Transcription factor 6 like 2 (mitochondrial transcription factor), Tra
Gene ID
7019
Swiss Prot
Q00059
Reactivity
Human
Immunogen
A synthetic peptide of human mtTFA
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC-P, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
300 μg/mL
Dilution
WB 1:1000-1:2000, IHC 1:50-1:100, IF 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
149kDa
Observed Molecular Weight
115kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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