Recombinant Cofilin Monoclonal Antibody
This is a Recombinant Cofilin Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Cofilin is a ubiquitous actin-binding protein required for the reorganization of actin filaments. It is a member of ADF (actin-depolymerizing factor) /cofilin family that is a key regulator of actin dynamics and essential for cellular motility, cytokinesis, and endocytosis. Cofilin activity is tightly regulated by phosphorylation and dephosphorylation. Phosphorylation at Ser3 can inhibit its activity, also causing translocation from the nucleus to the cytoplasm.
Synonyms
18 kDa phosphoprotein, CFL 1, CFL, CFL1, COF1, Cofilin 1, Cofilin 1 non muscle, Cofilin, Cofilin non muscle isoform, Cofilin-1, epididymis secretory protein Li 15, HEL-S-15, non-muscle isoform, p18
Gene ID
1072
Swiss Prot
P23528
Reactivity
Human
Immunogen
A synthetic peptide of human Cofilin
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC-P, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000, IHC 1:50-1:200, IF 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
73kDa
Observed Molecular Weight
80kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Frequently Asked Questions
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