NADPH oxidase 4 (NOX4) Polyclonal Antibody
This is a NADPH oxidase 4 (NOX4) Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS) . The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Synonyms
NOX4, KOX, KOX-1, RENOX
Gene ID
50507
Swiss Prot
Q9NPH5
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein of human NADPH oxidase 4
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:100
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
250kDa
Observed Molecular Weight
251KDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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