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DBT Polyclonal Antibody

This is a DBT Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Synonyms

E2, E2B, BCATE2, BCKADE2, BCKAD-E2, BCKDH-E2, BCOADC-E2

Gene ID

1629

Swiss Prot

P11182

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human DBT

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000, IHC 1:50-1:200, IF 1:50-1:200

Buffer

PBS with 0.05% proclin300,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

24kDa

Observed Molecular Weight

35KDa/75KDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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