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PKM2-specific Polyclonal Antibody

This is a PKM2-specific Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.

Synonyms

PK3, TCB, p58, OIP3, PKM2, CTHBP, THBP1

Gene ID

5315

Swiss Prot

P14618

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human PKM2-specific

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000, IF 1:50-1:200

Buffer

PBS with 0.01% thiomersal,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

56kDa/57kDa/58kDa

Observed Molecular Weight

58kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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