F11R Polyclonal Antibody
This is a F11R Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Synonyms
F11R, CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1
Gene ID
50848
Swiss Prot
Q9Y624
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human F11R
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
68kDa
Observed Molecular Weight
69KDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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