(KD Validated) eIF4E Polyclonal Antibody
This is a (KD Validated) eIF4E Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
Synonyms
AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F, eIF-4E, EIF4E
Gene ID
1977
Swiss Prot
P06730
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human eIF4E
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IF 1:50-1:200, IHC 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
58kDa/59kDa/60kDa
Observed Molecular Weight
65KDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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