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(KO Validated) SQSTM1/p62 Polyclonal Antibody

This is a (KO Validated) SQSTM1/p62 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Synonyms

SQSTM1, A170, DMRV, FTDALS3, NADGP, OSIL, PDB3, ZIP3, p60, p62, p62B, sequestosome-1

Gene ID

8878

Swiss Prot

Q13501

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human SQSTM1/p62

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000, IHC 1:50-1:200, IF 1:50-1:200

Buffer

PBS with 0.05% proclin300,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

25kDa/33kDa/39kDa

Observed Molecular Weight

67KDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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