Tildipirosin

Tildipirosin, a long-acting macrolide, has antibiotic activity.

Product Specifications

CAS Number

[328898-40-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Tildipirosin.html

Purity

99.95

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O[C@H]([C@H]([C@H](O)[C@@H](C)O1)N(C)C)[C@]1([H])O[C@H]2[C@H](C[C@H](C(/C=C/C(C)=C/[C@H](CN3CCCCC3)[C@@H](CC)OC(C[C@@H](O)[C@@H]2C)=O)=O)C)CCN4CCCCC4

Molecular Formula

C41H71N3O8

Molecular Weight

734.02

Precautions

H302, H315, H319, H335

References & Citations

[1]Rose M, et al. A microbiological assay to estimate the antimicrobial activity of parenteral tildipirosin against foodborne pathogens and commensals in the colon of beef cattle and pigs. J Vet Pharmacol Ther. 2016 Jun;39 (3) :277-86.|[2]Confer AW, et al. Clinical disease and lung lesions in calves experimentally inoculated with Histophilus somni five days after metaphylactic administration of tildipirosin or tulathromycin. Am J Vet Res. 2016 Apr;77 (4) :358-66.|[3]Angell JW, et al. In vitro susceptibility of contagious ovine digital dermatitis associated Treponema spp. isolates to antimicrobial agents in the UK. Vet Dermatol. 2015 Dec;26 (6) :484-7, e114-5.|[4]Michael GB, et al. Increased MICs of gamithromycin and tildipirosin in the presence of the genes erm (42) and msr (E) -mph (E) for bovine Pasteurella multocida and Mannheimia haemolytica. J Antimicrob Chemother. 2012 Jun;67 (6) :1555-7.