Human CD79A&CD79B Heterodimer Protein, Mouse IgG2a Fc, Flag Tag&Mouse IgG2a Fc, His Tag (MALS verified)
CD79a and CD79b heterodimers are the important signaling components of B cell receptor (BCR) complex which plays a crucial role in B cell development and antibody production. BCR complexes are composed of a ligand-binding receptor (membrane immunoglobulin; mIg), non-covalently associated with the signaling com-ponent, a disulfide-linked heterodimer of CD79a (Igα) and CD79b (Igβ) . Both CD79 subunits consist of an Ig-like domain, a transmembrane (TM) region, and a longer cytoplasmic tail (CYT) containing an immune-receptor tyrosine-based activation motif (ITAM) .
Product Specifications
Background
Specifications
Accession Number
P11912-1 (CD79A) & P40259-1 (CD79B)
Expression Region
Leu 33 - Arg 143 (CD79A) & Ala 29 - Asp 159 (CD79B)
Host
HEK293
Target
CD79A & CD79B
Conjugation
Unconjugated
Tag
C-mFc (mIgG2a) & C-Flag | C-mFc (mIgG2a) & C-10xHis
Source
Human
Stability
Endotoxin
0.1 EU per μg
Purity
95%
Bioactivity
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
43.8 kDa & 46.7 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*2
Host or Source
HEK293
Species
Human
Protein ID
P11912-1 (CD79A) & P40259-1 (CD79B)
Preservative
Trehalose
Frequently Asked Questions
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