What is the catalog number for Anti-Nitrotyrosine (mouse monoclonal) (clone EM-30)?

The catalog number for Anti-Nitrotyrosine (mouse monoclonal) (clone EM-30) is AS21 4622.

What sizes are available for Anti-Nitrotyrosine (mouse monoclonal) (clone EM-30)?

Anti-Nitrotyrosine (mouse monoclonal) (clone EM-30) is available in the following size(s): 0.1 mg.

Is Anti-Nitrotyrosine (mouse monoclonal) (clone EM-30) in stock?

Anti-Nitrotyrosine (mouse monoclonal) (clone EM-30) is currently made to order / not held in immediate stock. Contact us for lead time.

Anti-Nitrotyrosine (mouse monoclonal) (clone EM-30)

Product Specifications

Background

Nitrotyrosine can be detected in proteins from a variety of tissues, usually in association with pathological conditions. Reaction of nitric oxide with superoxide produces peroxynitrite, which can undergo heterolytic cleavage into nitronium and hydroxyl ions. Nitration of tyrosine residues by nitronium ion forms nitrotyrosine groups in the respective proteins. Nitrotyrosine is thus a marker for inflammation-associated tissue damage.

CAS Number

9007-83-4

HS Code

38221900

Host

Mouse

Reactivity

Nitrotyrosine

Immunogen

NO2-Tyr-CH2-Thyroglobulin

Clonality

Monoclonal

Applications

Immunohistochemistry (IHC) paraffin, Iimmunohistochemistry (IHC) frozen sections, Western blot (WB)

Field of Research

Human Oxidative Stress

Dilution

(IHC) paraffin: 10 µg/ml; positive tissue: colon cancer epithelium, prostate hyperplasia. (IHC) frozen sections: 10 µg/ml; positive tissue: colon cancer epithelium, prostate hyperplasia. (WB) : positive control: NO2-BSA, NO2-HSA.

Purity

Immunoglobulin purified on Protein A.

Format

Liquid at 1 mg/ml.

Additionnal Information

This antibody detects nitrotyrosine group in biological material, It can be used as a marker for peroxynitrite formation in particular tissues

References & Citations

To be added when available, antibody released in October 2021.

Storage Conditions

Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.