Anti-RFa1/Rpa1 | Replication factor protein 1 (Saccharomyces cerevisiae)
Product Specifications
Background
Rfa1 (Replication Factor A protein 1)as part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication.
Host
Rabbit
Reactivity
Saccharomyces cerevisiae
Immunogen
Purified, recombinant Rfa1 protein (without a tag) fromSaccharomyces cerevisiae, UniProt:P22336
Clonality
Polyclonal
Applications
Immunooprecipitation (IP), Western blot (WB)
Dilution
1: 200 (IP), 1 : 2000 (WB)
Purity
Serum.Contains 0.05% sodium azide.
Format
Liquid
Molecular Weight
70.3 kDa
Storage Conditions
Store at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Product Datasheet
https://cdn.gentaur.com/products/451/6867f70a994c49e6dc66fb4d/datasheet/as21 4550.pdf
CAS Number
9007-83-4
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