Anti-PRO4,5 | Profilin-4,5 (clone mAbPRF45a (2-B8) )
Product Specifications
Background
Profilin is an actin monomer-binding protein, involved in the organization and reconstruction of the actin cytoskeleton in eukaryotes. Profilin also interacts with membrane polyphospho-inositides, the Arp 2/3 complex, short proline rich stretches, and other ligands.
CAS Number
9007-83-4
HS Code
38221900
Gene ID
816496
UniProt
Q38905
Host
Mouse
Reactivity
Arabidopsis thaliana, Arabidopsis thaliana
Not reactive in
No confirmed exceptions from predicted reactivity are currently known
Immunogen
Profilin 4 (PRF4) from Arabidopsis thaliana, UniProt: Q38905, TAIR: AT4G29340
Clonality
Monoclonal
Applications
Immunohistochemistry (IHC), Western blot (WB)
Field of Research
Cytoskeleton
Purity
IgG1 immunoglobulin purified on Protein G in 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) sodium azide.
Format
Liquid
Molecular Weight
14 kDa
Precautions
This antibody reacts with both, PRF4 (profilin 4) and PRF5 (profilin 5)
Additionnal Information
Exact working dilution needs to be determined by end user
References & Citations
Kandasamy, M.K., et al. (2002) . Plant profilin isovariants are distinctly regulated in vegetative and reproductive tissues. Cell Motil Cytoskeleton 52 (1) :22-32. McKinney, E.C., et al. (2001) Small changes in the regulation of one Arabidopsis profilin isovariant, PRF1, alter seedling development. Plant Cell 13 (5) : 1179-91.
Storage Conditions
Store at -20°C, Make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Isotype
IgG1
Documents
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