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Anti-PRO4,5 | Profilin-4,5 (clone mAbPRF45a (2-B8) )

Product Specifications

Background

Profilin is an actin monomer-binding protein, involved in the organization and reconstruction of the actin cytoskeleton in eukaryotes. Profilin also interacts with membrane polyphospho-inositides, the Arp 2/3 complex, short proline rich stretches, and other ligands.

CAS Number

9007-83-4

HS Code

38221900

Gene ID

816496

UniProt

Q38905

Host

Mouse

Reactivity

Arabidopsis thaliana, Arabidopsis thaliana

Not reactive in

No confirmed exceptions from predicted reactivity are currently known

Immunogen

Profilin 4 (PRF4) from Arabidopsis thaliana, UniProt: Q38905, TAIR: AT4G29340

Clonality

Monoclonal

Applications

Immunohistochemistry (IHC), Western blot (WB)

Field of Research

Cytoskeleton

Purity

IgG1 immunoglobulin purified on Protein G in 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) sodium azide.

Format

Liquid

Molecular Weight

14 kDa

Precautions

This antibody reacts with both, PRF4 (profilin 4) and PRF5 (profilin 5)

Additionnal Information

Exact working dilution needs to be determined by end user

References & Citations

Kandasamy, M.K., et al. (2002) . Plant profilin isovariants are distinctly regulated in vegetative and reproductive tissues. Cell Motil Cytoskeleton 52 (1) :22-32. McKinney, E.C., et al. (2001) Small changes in the regulation of one Arabidopsis profilin isovariant, PRF1, alter seedling development. Plant Cell 13 (5) : 1179-91.

Storage Conditions

Store at -20°C, Make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Isotype

IgG1

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