Anti-ASyM | Mouse anti-human alpha synuclein N-terminal (clone number 4,2)
Product Specifications
Background
Alpha-synucleinis normally an unstructured soluble protein that can aggregate to form insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson's disease, dementia with Lewy-bodies, and multiple system atrophy.
Host
Mouse
Reactivity
Human
Not reactive in
No confirmed exceptions from predicted reactivity are currently known
Immunogen
Synthetic peptide derived from human alpha-synuclein N-terminal Met1-Val15
Clonality
Monoclonal
Applications
Dot blot (Dot), ELISA (ELISA), Immunohistochemistry (IHC)
Dilution
1-2 µg/mL (Dot), 2-4 µg/mL (ELISA capture), 10 µg/mL (IHC)
Purity
Immunogen affinity purified serum in PBS pH 7.4.
Format
Lyophilized
Reconstitution
For reconstitution add 50 µl of sterile water
Molecular Weight
14 kDa
References & Citations
Tanudjojoet al. (2021) Phenotypic manifestation of α-synuclein strains derived from Parkinson's disease and multiple system atrophy in human dopaminergic neurons. Nat Commun. 2021 Jun 21;12(1):3817. doi: 10.1038/s41467-021-23682-z. PMID: 34155194; PMCID: PMC8217249.
Storage Conditions
For short time storage add sodium azide and store at +4°C. For long time storage store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Product Datasheet
https://cdn.gentaur.com/products/451/6867f70b994c49e6dc66fbf4/datasheet/as13 2719.pdf
CAS Number
9007-83-4
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