Anti-Abeta (1-42) | Amyloid-beta peptide 1-42

Product Specifications

Background

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P05067

CAS Number

9007-83-4

HS Code

38221900

Host

Rabbit

Reactivity

Human

Not reactive in

No confirmed exceptions from predicted reactivity are currently known

Immunogen

Synthetic peptide chosen from human Abeta (1-42) protein. Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A

Clonality

Polyclonal

Applications

Dot Blot (Dot), ELISA (ELISA), Western blot (WB)

Field of Research

Alzheimer's disease

Dilution

1 : 1000 (Dot), 1 : 3000 (ELISA), 1 : 1000 (WB)

Purity

Serum

Format

Lyophilized

Reconstitution

For reconstitution add 100 µl of sterile water

Molecular Weight

4.5 kDa

Precautions

The antibody can detect Abeta(1-42), Abeta(1-28) Abeta(1-20) and Abeta(1-17)

Storage Conditions

Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.