Anti-Abeta (1-42) | Amyloid-beta peptide 1-42
Product Specifications
Background
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P05067
CAS Number
9007-83-4
HS Code
38221900
Host
Chicken
Reactivity
Human
Not reactive in
No confirmed exceptions from predicted reactivity are currently known
Immunogen
Synthetic peptide chosen from human Abeta (1-42) protein, Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A
Clonality
Polyclonal
Applications
Dot Blot (Dot), ELISA (ELISA)
Field of Research
Alzheimer's disease
Dilution
1 : 1000 (Dot), 1 : 500 (ELISA)
Purity
Purified total IgY (chicken egg yolk immunoglobulin) in PBS pH 8. Contains 0.02 % sodium azide.
Format
Liquid
Molecular Weight
4.5 kDa
Precautions
The antibody can detect Abeta(1-42), but does not react with Abeta(1-28) Abeta(1-20) or Abeta(1-17)
Storage Conditions
Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Prediction Reactivity
Bovine, Chicken, Dog, Porcine, Rabbit
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