Phospho-PAK1 (Thr212) Polyclonal Antibody
This is a Phospho-PAK1 (Thr212) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
Synonyms
ADRB2, Alpha PAK, Alpha-PAK, MGC130000, MGC130001, p21 activated kinase 1, p21 protein (Cdc42/Rac) activated kinase 1, p21-activated kinase 1, p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related), p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast), p65 PAK
Swiss Prot
Q13153
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human PAKα around the phosphorylation site of Thr212
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Phospho-Specific Antibody
Applications
WB, IHC-p, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
61 kDa
Observed Molecular Weight
65 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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