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CBX3 Monoclonal Antibody

This is a CBX3 Monoclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks.

Synonyms

CBX 3, CBX3, CBX3, Chromobox homolog 3 (HP1 gamma homolog, Drosophila), Chromobox homolog 3, Chromobox protein homolog 3, GAMMA, HECH, Heterochromatin like protein 1, Heterochromatin protein 1 homolog gamma, Heterochromatin protein HP1 gamma, HP1 gamma, HP1 gamma homo

Swiss Prot

Q13185

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein of HP-1γ

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Monoclonal Antibody

Applications

WB, IHC-p

Purification Method

Protein A purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-2000, IHC 1:50-300

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Observed Molecular Weight

24 kDa

Host or Source

Mouse

Isotype

IgG

Available Sizes

Curated Selection

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