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Crystallin-alpha C Monoclonal Antibody

This is a Crystallin-alpha C Monoclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Synonyms

Alpha crystallin C chain, Alpha-crystallin C chain, Charcot Marie Tooth disease axonal type 2L, Charcot Marie Tooth disease spinal, CMT2L, CRYAC, DHMN 2, DHMN2, E2 induced gene 1 protein, E2-induced gene 1 protein, E2IG1, H11, Heat shock 22kDa protein 8, Heat shock 27

Swiss Prot

Q9UJY1

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Monoclonal Antibody

Applications

WB

Purification Method

Protein A purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:1000-2000

Buffer

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Observed Molecular Weight

22 kDa

Host or Source

Mouse

Isotype

IgG

Available Sizes

Curated Selection

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