Crystallin-alpha C Monoclonal Antibody
This is a Crystallin-alpha C Monoclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Synonyms
Alpha crystallin C chain, Alpha-crystallin C chain, Charcot Marie Tooth disease axonal type 2L, Charcot Marie Tooth disease spinal, CMT2L, CRYAC, DHMN 2, DHMN2, E2 induced gene 1 protein, E2-induced gene 1 protein, E2IG1, H11, Heat shock 22kDa protein 8, Heat shock 27
Swiss Prot
Q9UJY1
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Protein
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
WB
Purification Method
Protein A purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:1000-2000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Observed Molecular Weight
22 kDa
Host or Source
Mouse
Isotype
IgG
Available Sizes
Curated Selection
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