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TBP Monoclonal Antibody

This is a TBP Monoclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.

Synonyms

GTF2D, GTF2D1, HDL4, SCA17, TATA binding factor, TATA box binding protein, TATA box factor, TATA sequence binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, TATA-box-binding protein, TBP, TBP, TFIID, Transcription initiation factor TFI

Swiss Prot

P20226

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Monoclonal Antibody

Applications

WB

Purification Method

Protein A purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:1000-2000

Buffer

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Observed Molecular Weight

35-45 kDa

Host or Source

Mouse

Isotype

IgG

Available Sizes

Curated Selection

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