CBX5 Monoclonal Antibody
This is a CBX5 Monoclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synonyms
Antigen p25, CBX5, CBX5, CG8409, Chromobox 5, Chromobox homolog 5 (HP1 alpha homolog, Drosophila), Chromobox homolog 5, Chromobox protein homolog 5, Epididymis luminal protein 25, HEL25, Heterochromatin protein 1 alpha, Heterochromatin protein 1, Heterochromatin prote
Swiss Prot
P45973
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Protein of HP-1α
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
WB, IHC-p
Purification Method
Protein A purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-2000, IHC 1:50-300
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Observed Molecular Weight
22 kDa
Host or Source
Mouse
Isotype
IgG
Available Sizes
Curated Selection
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