XRCC4 Monoclonal Antibody
This is a XRCC4 Monoclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V (D) J recombination. Binds to DNA and to DNA ligase IV (LIG4) . The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Synonyms
DNA double strand break repair and V (D) J recombination protein XRCC4, DNA repair protein XRCC4, SSMED, X ray repair complementing defective repair in Chinese hamster cells 4, X ray repair cross complementing 4, X ray repair cross complementing protein 4, X-ray
Swiss Prot
Q13426
Reactivity
Human
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
WB, IHC-p, IF, IP
Purification Method
Protein A purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
38 kDa
Observed Molecular Weight
38 kDa
Host or Source
Mouse
Isotype
IgG
Available Sizes
Curated Selection
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