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XRCC4 Monoclonal Antibody

This is a XRCC4 Monoclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V (D) J recombination. Binds to DNA and to DNA ligase IV (LIG4) . The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Synonyms

DNA double strand break repair and V (D) J recombination protein XRCC4, DNA repair protein XRCC4, SSMED, X ray repair complementing defective repair in Chinese hamster cells 4, X ray repair cross complementing 4, X ray repair cross complementing protein 4, X-ray

Swiss Prot

Q13426

Reactivity

Human

Immunogen

Synthetic Peptide

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Monoclonal Antibody

Applications

WB, IHC-p, IF, IP

Purification Method

Protein A purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

38 kDa

Observed Molecular Weight

38 kDa

Host or Source

Mouse

Isotype

IgG

Available Sizes

Curated Selection

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