CD45 Monoclonal Antibody
This is a CD45 Monoclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.
Synonyms
B220, CD 45, CD45, CD45 antigen, CD45R, GP180, L-CA, LCA, Leukocyte common antigen, loc, Ly-5, LY5, Ly5, homolog of, Lyt-4, OTTHUMP00000033813, OTTHUMP00000033816, OTTHUMP00000033817, OTTHUMP00000038574, Protein tyrosine phosphatase receptor type c polypeptide, Protein tyros
Swiss Prot
P08575
Reactivity
Human
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
WB, IHC-p
Purification Method
Protein A purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-300
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
147 kDa
Observed Molecular Weight
147 kDa
Host or Source
Mouse
Isotype
IgG
Available Sizes
Curated Selection
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