GPM6A Polyclonal Antibody
This is a GPM6A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Neuronal membrane glycoprotein M6-ais aproteinthat in humans is encoded by theGPM6Agene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs) ; enhances internalization and recycling of mu-type opioid receptor.
Synonyms
GPM6A, GPM6, M6A
Gene ID
2823
Swiss Prot
P51674
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human GPM6A (NP_005268.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
29 kDa/30 kDa/31 kDa
Observed Molecular Weight
31 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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