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GPM6A Polyclonal Antibody

This is a GPM6A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Neuronal membrane glycoprotein M6-ais aproteinthat in humans is encoded by theGPM6Agene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs) ; enhances internalization and recycling of mu-type opioid receptor.

Synonyms

GPM6A, GPM6, M6A

Gene ID

2823

Swiss Prot

P51674

Reactivity

Human, Mouse

Immunogen

A synthetic peptide of human GPM6A (NP_005268.1) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000 IHC 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

29 kDa/30 kDa/31 kDa

Observed Molecular Weight

31 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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