MKL1 Polyclonal Antibody
This is a MKL1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.
Synonyms
MKL1, BSAC, MAL, MRTF-A
Gene ID
57591
Swiss Prot
Q969V6
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human MKL1 (NP_065882.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
98 kDa
Observed Molecular Weight
145 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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