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CFL2 Polyclonal Antibody

This is a CFL2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

Synonyms

CFL2, NEM7, cofilin-2

Gene ID

1073

Swiss Prot

Q9Y281

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human CFL2 (NP_068733.1) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000 IF 1:50-1:100

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

16 kDa/18 kDa

Observed Molecular Weight

18 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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