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NBN Polyclonal Antibody

This is a NBN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Synonyms

NBN, AT-V1, AT-V2, ATV, NBS, NBS1, P95, nibrin

Gene ID

4683

Swiss Prot

O60934

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human NBN

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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