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KU70 Polyclonal Antibody

This is a KU70 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Synonyms

XRCC6, CTC75, CTCBF, G22P1, KU70, ML8, TLAA

Gene ID

2547

Swiss Prot

P12956

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human KU70 (NP_001460.1) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

65 kDa/69 kDa

Observed Molecular Weight

70 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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