KU70 Polyclonal Antibody
This is a KU70 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Synonyms
XRCC6, CTC75, CTCBF, G22P1, KU70, ML8, TLAA
Gene ID
2547
Swiss Prot
P12956
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human KU70 (NP_001460.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
65 kDa/69 kDa
Observed Molecular Weight
70 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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