Cleomiscosin A
Cleomiscosin A is a coumarino-lignoid from branch of Macaranga adenantha. Cleomiscosin A is active against TNF-alpha secretion of the mouse peritoneal macrophages[1][2].
Product Specifications
CAS Number
76948-72-6
UNSPSC
12352005
Target
TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cleomiscosin-a.html
Purity
99.15
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
COC1=CC(C=CC2=O)=C(O2)C3=C1O[C@H](C4=CC(OC)=C(O)C=C4)[C@@H](CO)O3
Molecular Formula
C20H18O8
Molecular Weight
386.35
References & Citations
[1]Sharma S, et al. Synthesis and anti-inflammatory activity of derivatives of coumarino-lignoid, cleomiscosin A and its methyl ether. Eur J Med Chem. 2010;45 (11) :5150-5156.|[2]Ma M, et al. Zhongguo Zhong Yao Za Zhi. 2007;32 (12) :1175-1179.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
TNFRSF5/CD40
Available Sizes
Frequently Asked Questions
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