Cleomiscosin A

Cleomiscosin A is a coumarino-lignoid from branch of Macaranga adenantha. Cleomiscosin A is active against TNF-alpha secretion of the mouse peritoneal macrophages[1][2].

Product Specifications

CAS Number

[76948-72-6]

UNSPSC

12352005

Target

TNF Receptor

Type

Natural Products

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cleomiscosin-a.html

Purity

99.15

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

COC1=CC(C=CC2=O)=C(O2)C3=C1O[C@H](C4=CC(OC)=C(O)C=C4)[C@@H](CO)O3

Molecular Formula

C20H18O8

Molecular Weight

386.35

References & Citations

[1]Sharma S, et al. Synthesis and anti-inflammatory activity of derivatives of coumarino-lignoid, cleomiscosin A and its methyl ether. Eur J Med Chem. 2010;45 (11) :5150-5156.|[2]Ma M, et al. Zhongguo Zhong Yao Za Zhi. 2007;32 (12) :1175-1179.