CD177 Polyclonal Antibody
This is a CD177 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes a glycosyl-phosphatidylinositol (GPI) -linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.
Synonyms
CD177, HNA-2a, HNA2A, NB1, NB1 GP, PRV-1, PRV1, NB1GP
Gene ID
57126
Swiss Prot
Q8N6Q3
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human CD177 (NP_065139.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
15 kDa/27 kDa/46 kDa
Observed Molecular Weight
45 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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