PTPRN Polyclonal Antibody
This is a PTPRN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.
Synonyms
PTPRN, IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Gene ID
5798
Swiss Prot
Q16849
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PTPRN (NP_001186693.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
96 kDa/102 kDa/105 kDa
Observed Molecular Weight
66 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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