(KO Validated) HuR / ELAVL1 Polyclonal Antibody
This is a (KO Validated) HuR / ELAVL1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
Synonyms
ELAV1, HUR, Hua, MelG, HuR / ELAVL1, ELAVL1
Gene ID
1994
Swiss Prot
Q15717
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human HuR / ELAVL1 (NP_001410.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
36 kDa/38 kDa
Observed Molecular Weight
36 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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