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LGI1 Polyclonal Antibody

This is a LGI1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.

Synonyms

LGI1, ADLTE, ADPAEF, ADPEAF, EPITEMPIN, EPT, ETL1, IB1099

Gene ID

9211

Swiss Prot

O95970

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human LGI1 (NP_005088.1) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

33 kDa/58 kDa/63 kDa

Observed Molecular Weight

64 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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