GMNN Polyclonal Antibody
This is a GMNN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.
Synonyms
GMNN, Gem, MGORS6, geminin
Gene ID
51053
Swiss Prot
O75496
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human GMNN (NP_056979.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
23 kDa
Observed Molecular Weight
24 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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