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PIDD Polyclonal Antibody

This is a PIDD Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6) -associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.

Synonyms

PIDD1, LRDD, PIDD

Gene ID

55367

Swiss Prot

Q9HB75

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human PIDD (NP_665893.2) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

33 kDa/37 kDa/58 kDa/66 kDa/82 kDa/97 kDa/99 kDa

Observed Molecular Weight

100-110 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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