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PSMA7 Polyclonal Antibody

This is a PSMA7 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9.

Synonyms

PSMA7, C6, HEL-S-276, HSPC, RC6-1, XAPC7

Gene ID

5688

Swiss Prot

O14818

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human PSMA7 (NP_002783.1) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

16 kDa/20 kDa/27 kDa

Observed Molecular Weight

30 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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