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SETD2 Polyclonal Antibody

This is a SETD2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

Synonyms

SETD2, HBP231, HIF-1, HIP-1, HSPC069, HYPB, KMT3A, LLS, SET2, p231HBP

Gene ID

29072

Swiss Prot

Q9BYW2

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human SETD2 (NP_054878.5) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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