Riluzole (Standard)

Riluzole (Standard) is the analytical standard of Riluzole. This product is intended for research and analytical applications. Riluzole is an anticonvulsant agent and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.

Product Specifications

CAS Number

[1744-22-5]

Product Name Alternative

PK 26124 (Standard)

UNSPSC

12352005

Hazard Statement

H300

Target

GABA Receptor; Reference Standards; Sodium Channel

Type

Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/riluzole-standard.html

Purity

99.82

Smiles

NC1=NC2=CC=C(OC(F)(F)F)C=C2S1

Molecular Formula

C8H5F3N2OS

Molecular Weight

234.20

Precautions

H300

References & Citations

[1]He Y, et al. Neuroprotective agent riluzole potentiates postsynaptic GABA (A) receptor function. Neuropharmacology. 2002 Feb;42 (2) :199-209.|[2]Thompson JM, et al. Small-conductance calcium-activated potassium (SK) channels in the amygdala mediate pain-inhibiting effects of clinically available riluzole in a rat model of arthritis pain. Mol Pain. 2015 Aug 28;11:51.