LXR alpha Polyclonal Antibody
This is a LXR alpha Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms
NR1H3, LXR-a, LXRA, RLD-1, LXR alpha
Gene ID
10062
Swiss Prot
Q13133
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human LXR alpha (NP_005684.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
43 kDa/45 kDa/50 kDa
Observed Molecular Weight
50 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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