EIF6 Polyclonal Antibody
This is a EIF6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene.
Synonyms
EIF6, CAB, EIF3A, ITGB4BP, b (2) gcn, eIF-6, p27 (BBP), p27BBP
Gene ID
3692
Swiss Prot
P56537
Reactivity
Human
Immunogen
Recombinant fusion protein of human EIF6 (NP_852133.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
23 kDa/26 kDa
Observed Molecular Weight
27 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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